Roots Magazine 2/2015 – Use and abuse of antibiotics
Steven Morrow DDS
For the past 80 years, antibiotic therapy has played a major role in the treatment of bacterial infectious diseases.
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Since the discovery of penicillin in 1928 by Fleming and sulfanilamide in 1934 by Domagk, the entire world has benefited from one of the greatest medical advancements in history. The discovery of safe, systemic antibiotics has been a major factor in the control of infectious diseases and, as such, has increased life expectancy and the quality of life for millions of people.
According to the Centers for Disease Control and Prevention, life expectancy of individuals in the United States born in 1900 was 47 years, while those born in 2005 is projected to be 78 years. At the beginning of the 20th century, the infant (< 1 year) mortality rate in the United States was 100/1,000 live births compared to 6.7/1,000 in 2006. The major reason for these phenomenal achievements has been the ability to control infectious diseases.3
- Describe the factors responsible for the development of the current state of antibacterial drug resistance.
- Explain what nosocomial infections are and what affect they have on the community as a whole.
- Discuss the proper clinical use of antibiotics in dentistry.]
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For additional reading on the topic, please refer to:
- Health, United States, 2009: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2009.
- Health, United States, 2010: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, April 2010.
- Pallasch TJ. Pharmacology of Anxiety, Pain and Infection. In: Endodontics. 4th ed. Williams and Wilkins, Malvern, PA, 1994.
- ADA Council on Scientific Affairs. Combating antibiotic resistance. J Am Dent Assoc 2004;135:484.
- Nicolle L. Nosocomial Infections. Gale Encyclopedia of Public Health. Macmillan Reference USA, Farmington Hills, MI, 2002.
- Sweeney LC, Jayshree D, Chambers PA, Heritage J. Antibiotic resistance in general dental practice—a cause for concern. J Antimicrobial Chemotherapy 2004;53:567.
- Epstein JB, Chong S, Le ND. A survey of antibiotic use in dentistry. J Am Dent Assoc 2000;131:1600.
- Associated Press. Killer superbug solution discovered in Norway. www.msnbc.com, December 2009.
- ADA Council on Scientific Affairs. Antibiotic use in dentistry. J Am Dent Assoc 1997;128:648.
- Wills A. Why we learn from our mistakes. J Cognitive Neuroscience 2007;19:1163.
- Pallasch TJ. Antibiotic myths and reality. J Cali Dent Assoc 1986;14:65.
Release date: 24 April 2015
Expiration date: 24 April 2018
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